Vascular SurgeryNeurology
Subclavian Steal Syndrome
Proximal subclavian stenosis → reverse flow in vertebral artery during arm exertion → posterior circulation symptoms.
Source: ESC; AHA
Step 1 of ~2
info
Recognise + Pathophysiology
Stenosis / occlusion of proximal subclavian artery (proximal to vertebral artery origin) — usually atherosclerotic; rarely Takayasu's, fibromuscular dysplasia, prior radiation, post-surgical.
During arm exertion, demand exceeds supply → blood 'stolen' from vertebral artery (retrograde flow) → posterior circulation insufficiency.
Features:
• Arm: claudication, weakness, paraesthesia, cold arm (with exertion).
• Asymmetric arm BP (>15 mmHg difference) and/or weak / absent radial pulse on affected side.
• Posterior circulation symptoms: vertigo, visual disturbance, syncope, ataxia, dysarthria — typically with arm exertion.
• Coronary-subclavian steal: angina post-CABG with LIMA graft + subclavian stenosis (chest pain on arm exertion).
Workup:
• Bilateral arm BPs.
• Doppler USS subclavian + vertebral arteries.
• CT / MR angiography.
• Catheter angiography (gold standard, also therapeutic).
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Aciclovir 800mg Tablets (Ramsay Hunt Syndrome / Herpes Zoster Oticus) · Antiviral — nucleoside analogue (herpes zoster treatment)
- Pramipexole (Restless Legs Syndrome — Elderly) · Dopamine Agonist (D2/D3 Receptor)
- Lamivudine · Nucleoside reverse transcriptase inhibitor
- Nevirapine · Non-nucleoside reverse transcriptase inhibitor (1st gen)
- Tenofovir alafenamide · Nucleotide reverse transcriptase inhibitor (prodrug)
- Tenofovir disoproxil · Nucleotide reverse transcriptase inhibitor
Pathways
Decision support only. Always apply local guidelines and clinical judgement.