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Renal

Autosomal Dominant Polycystic Kidney Disease

Diagnosis (Pei-Ravine criteria), risk stratification (Mayo class), tolvaptan, cardiovascular & extra-renal complications.

Source: KDIGO 2024; UK Kidney Association 2024

Step 1 of ~4
info

Diagnosis

Pei-Ravine criteria for at-risk patients with positive family history: • Age 15–39: ≥3 unilateral or bilateral cysts. • Age 40–59: ≥2 cysts in each kidney. • Age ≥60: ≥4 cysts in each kidney. If no FH: ≥10 cysts each kidney + extra-renal features support. Genetic testing if atypical or for transplant donor screening: PKD1 (85%), PKD2 (15%).

Related

Curated clinical cross-links plus same-class fallbacks.

Decision support only. Always apply local guidelines and clinical judgement.