PaediatricsEmergency Medicine
Paediatric Sepsis
NICE NG143 / RCPCH — recognition with traffic light + paediatric sepsis 6, antibiotics within 1h, age-specific physiology, escalation triggers.
Source: NICE NG143; RCPCH/UK Sepsis Trust 2024; APLS 6th Ed
Step 1 of ~5
info
Recognise — Age-Adjusted Physiology
Suspect in any child with infection + ≥1 of: ALOC, mottled/ashen/cyanotic skin, non-blanching rash, ↓ urine output, age-adjusted tachycardia or tachypnoea, hypotension (late sign — ominous). Always check capillary blood glucose. NEVER delay antibiotics for paediatric sepsis. Verify all paediatric drug doses against BNF for Children (BNFc) before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Retinol palmitate with white soft paraffin, light liquid paraffin, liquid paraffin and wool fat · Ocular lubricant ointment
- Ceftriaxone (Paediatric) · Third-Generation Cephalosporin — Meningitis / Sepsis / Community-Acquired Pneumonia
- Gentamicin (Paediatric) · Aminoglycoside — Neonatal Sepsis / Gram-Negative Infections in Children
- Neostigmine · Anticholinesterase (Reversal Agent)
- Prilocaine · Local Anaesthetic (Amide)
- Mepivacaine with adrenaline · Amide LA + vasoconstrictor
Decision support only. Always apply local guidelines and clinical judgement.