Endocrinology
Hashimoto's / Hypothyroidism Management
Confirm with TSH + fT4 + TPO antibody, levothyroxine titration, special situations (pregnancy, elderly, ischaemic heart disease).
Source: NICE NG145; BTA 2023
Step 1 of ~4
info
Diagnosis
Symptoms: fatigue, weight gain, cold intolerance, constipation, depression, dry skin, hair loss, menstrual irregularity, hoarse voice, slow reflexes, bradycardia. Confirm: TSH ↑ + fT4 ↓ (overt hypothyroid). Subclinical: TSH 4–10 + normal fT4. TPO antibodies for autoimmune Hashimoto's. Other: FBC (often macrocytic anaemia), lipids (often ↑), CK (↑ in severe).
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
- Bisoprolol (Heart Failure in Elderly) · Selective beta-1 blocker
- Levothyroxine (Elderly) · Thyroid Hormone
- Entacapone · COMT Inhibitor — Parkinson's Disease
- Natalizumab · Disease-Modifying Therapy — MS (Anti-VLA-4 Monoclonal Antibody)
- Methotrexate (Ectopic) · Antimetabolite (Ectopic Pregnancy Management)
- Inebilizumab (Anti-CD19 — IgG4-Related Disease) · Anti-CD19 Monoclonal Antibody (B-Cell Depleting)
Pathways
- Diabetic Ketoacidosis (DKA) · JBDS 2013 / Joint British Diabetes Societies; NICE NG17
- Adult Hypoglycaemia (Treated Diabetes) · JBDS-IP (2023): Hospital Management of Hypoglycaemia
- Adrenal Crisis · Society for Endocrinology Emergency Guidance (2024)
- Type 2 Diabetes Management · NICE NG28 2022
- Hyperthyroidism Management · BTA / ETA 2018
- Adrenal Insufficiency · Society of Endocrinology / ESE 2016
Decision support only. Always apply local guidelines and clinical judgement.