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LAMA + LABA

Umeclidinium with vilanterol

Brand names: Anoro Ellipta

Adult dose

Dose: 1 inhalation (62.5/25 micrograms) OD
Route: Inhaled
Frequency: OD

Clinical pearls

  • COPD maintenance per NICE NG115
  • Not for asthma without ICS

Contraindications

  • Hypersensitivity
  • Untreated asthma without ICS

Side effects

  • Dry mouth
  • Headache
  • Tachycardia
  • Tremor
  • Hypokalaemia
  • Glaucoma

Interactions

  • β-blockers
  • Other antimuscarinics
  • QT-prolonging drugs
  • CYP3A4 inhibitors

Monitoring

  • Symptoms
  • Inhaler technique

Reference: BNF; NICE NG115; https://bnf.nice.org.uk/drugs/umeclidinium-with-vilanterol/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.