Non-selective NSAID
Flurbiprofen
Brand names: Strefen, Froben
Adult dose
Dose: PO 50–100mg BD–QDS (max 300mg/day). Lozenge (sore throat): 8.75mg every 3–6h, max 5/24h
Route: PO/Lozenge
Frequency: BD-QDS
Clinical pearls
- Lozenge for symptomatic sore throat; main systemic use as alternative NSAID
Contraindications
- Active GI bleeding/ulcer
- Severe heart failure
- Severe renal impairment
- Aspirin/NSAID hypersensitivity
- 3rd trimester pregnancy
Side effects
- GI upset/bleeding
- Renal impairment
- Cardiovascular events
- Bronchospasm in NSAID-sensitive asthma
Interactions
- Anticoagulants/antiplatelets
- ACEi/ARB
- Lithium
- Methotrexate
Reference: BNF; NICE NG84; https://bnf.nice.org.uk/drugs/flurbiprofen/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Drugs
Pathways
- Adult Upper Airway Obstruction (Stridor) · DAS 2015 unanticipated difficult airway; RCEM
- Epistaxis Management · ENT-UK / NICE
- Acute Otitis Media · NICE NG91 2018
- Tonsillitis and Sore Throat · NICE NG84 2018
- Benign Paroxysmal Positional Vertigo · NICE CG124 / AAO-HNS Guidelines
- Acute Rhinosinusitis · NICE NG79 2017 / EPOS 2020