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Oral ferrous iron

Ferrous fumarate

Brand names: Galfer, Fersaday, Fersamal

Adult dose

Dose: 210mg TDS (≈68mg elemental TDS); prophylaxis 210mg OD
Route: PO
Frequency: OD-TDS

Clinical pearls

  • Iron deficiency anaemia — alternate-day dosing (e.g. 200mg every other day) gives equal Hb response with fewer side effects (current evidence)

Contraindications

  • Iron overload
  • Haemochromatosis

Side effects

  • GI upset
  • Black stools
  • Constipation
  • Tooth staining (liquid)

Interactions

  • Tetracyclines, quinolones, levothyroxine, bisphosphonates, methyldopa (chelation; separate by ≥2h)
  • Antacids reduce absorption
  • Vitamin C improves absorption

Monitoring

  • Hb
  • Ferritin
  • TSAT

Reference: BNF; NICE CKS; Stoffel et al 2019 (alternate-day dosing); https://bnf.nice.org.uk/drugs/ferrous-fumarate/. Verify against your local formulary and the latest BNF before prescribing.

Related

Curated clinical cross-links plus same-class fallbacks.