Corticosteroid + aminoglycoside
Betamethasone with neomycin
Brand names: Betnesol-N, Vista-Methasone N
Adult dose
Dose: Skin: BD; Eye: 1–2 drops 2–6h; Ear: 2–3 drops TDS
Route: Topical / Otic / Ophthalmic
Frequency: Per indication
Clinical pearls
- NICE CKS Otitis externa / NG198 eczema
- Limit duration (≤7 days topical, ≤2 weeks ophthalmic without specialist)
- Resistance to neomycin common
Contraindications
- Untreated infection
- Perforated tympanic membrane (relative — ototoxicity)
- Glaucoma
- Hypersensitivity
Side effects
- Hypersensitivity
- Ototoxicity (perforated drum)
- Increased IOP / cataract (chronic eye use)
- Skin atrophy
Interactions
- Other ototoxic drugs
Monitoring
- IOP / hearing if extended use
- Skin response
Reference: BNF; NICE CKS Otitis externa; NICE NG198; ENT UK; https://bnf.nice.org.uk/drugs/betamethasone-with-neomycin/. Verify against your local formulary and the latest BNF before prescribing.
Related
Curated clinical cross-links plus same-class fallbacks.
Calculators
Pathways
- Suspicious Pigmented Lesion — Melanoma Pathway · NICE NG14 2015 / BAD
- Cellulitis and Erysipelas · NICE NG141 2019 / CREST
- Psoriasis — Severity Assessment and Step-Up Therapy · NICE NG153 2019 / BAD
- Atopic Eczema — Assessment and Step-Up Therapy · NICE NG95 2023
- Urticaria and Angioedema · BSACI / EAACI Guidelines 2022
- Acne Vulgaris — Grading and Treatment · NICE NG198 2021 / BAD