Infectious Disease Calculators

Quick SOFA (qSOFA) for rapid sepsis identification outside ICU. Score ≥2 warrants full assessment.

Pneumonia Severity Index (PSI) for stratifying CAP mortality risk. Patients in classes I–II can be treated as outpatients.

Estimates estimated HIV transmission risk per exposure type to counsel patients and guide PrEP/PEP decisions.

Diagnoses ventilator-associated pneumonia (VAP) and hospital-acquired pneumonia (HAP). Score >6 suggests VAP.

Multinational Association for Supportive Care in Cancer (MASCC) index for febrile neutropenia. Score ≥21 = low risk.

Identifies patients requiring antibiotic prophylaxis before dental procedures based on ESC/AHA guidelines.

WHO 2015 criteria for severe P. falciparum malaria requiring parenteral artesunate and ITU-level care.

UK-derived 5-item clinical score to predict Group A Strep pharyngitis and guide antibiotic prescribing. Validated in UK primary care. Endorsed by NICE NG84.

Predicts probability of septic arthritis vs transient synovitis in children with acute hip pain. Validated by Caird et al. with CRP enhancement.

Tuberculin Skin Test (Mantoux) interpretation for latent TB infection (LTBI) screening. Induration threshold varies by risk group per NICE / WHO.

Validated risk score identifying HIV-negative men who have sex with men (MSM) at highest risk for HIV acquisition who would benefit most from pre-exposure prophylaxis (PrEP). Derived from the EXPLORE cohort. Score 0–45; score ≥11 indicates high risk warranting PrEP discussion.

Structured risk stratification tool guiding post-exposure prophylaxis (PEP) decisions following occupational or non-occupational HIV exposure. Considers source HIV status, exposure type, and clinical context to determine PEP indication.

Evidence-based guide to CD4 count and viral load monitoring frequency in people living with HIV (PLHIV) on antiretroviral therapy (ART). Based on BHIVA HIV monitoring guidelines 2023. Helps determine appropriate review intervals.

Sequential Organ Failure Assessment (SOFA) score for organ dysfunction in ICU. Core of Sepsis-3 definition: sepsis = SOFA increase >=2.

Stratifies risk of AIDS-defining opportunistic infections based on CD4 count. Guides prophylaxis decisions and clinical monitoring.

Classifies dengue fever severity using WHO 2009 criteria. Guides fluid management, monitoring, and hospital admission decisions.

Rapid severity assessment for lower respiratory tract infections to guide antibiotic prescribing and admission decisions in community settings.

Identifies high-risk influenza patients requiring antiviral therapy (oseltamivir) and hospital-level care.

Guides antiviral therapy decision in chronic hepatitis B based on HBeAg status, viral load, ALT, and fibrosis stage.

Identifies patients at risk of TB treatment non-adherence to guide directly observed therapy (DOTS) allocation and social support.

Classifies malaria as uncomplicated vs severe per WHO 2015 criteria. Severe malaria (Plasmodium falciparum) requires IV artesunate, not oral therapy.

Diagnoses infective endocarditis using major and minor Duke criteria. Guides echocardiography, blood culture interpretation, and empirical antibiotic selection.

Predicts risk of specific opportunistic infections by CD4 count threshold. Guides prophylaxis and diagnostic priorities in HIV-positive patients.

Stratifies risk and guides urgent investigation in febrile returning travellers. Malaria must be excluded in all cases.

Grades C. difficile infection (CDI) severity using ESCMID/IDSA criteria. Guides fidaxomicin vs vancomycin vs bezlotoxumab vs surgery decisions.

Predicts risk of serious complications in febrile neutropenia. MASCC score >=21 identifies low-risk patients eligible for outpatient oral antibiotic management.

Assesses risk of active or congenital toxoplasmosis. Guides spiramycin/pyrimethamine-sulphadiazine therapy and neonatal screening.

Severity score in patients with bloodstream infection (Hilf 1989). Predicts mortality and used to stratify patients in clinical trials of new antibiotics. Sums 5 weighted variables (max 14).

Acute febrile reaction occurring within 24 h of antibiotic treatment for spirochaete infections (syphilis, leptospirosis, Lyme, relapsing fever). Categorise severity for management.